Comparative Study of Antidiabetic Activity and Oxidative Stress Induced by Zinc Oxide Nanoparticles and Zinc Sulfate in Diabetic Rats
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چکیده
منابع مشابه
Antidiabetic Activity of Zinc Oxide and Silver Nanoparticles on Streptozotocin-Induced Diabetic Rats
The use of nanoparticles in medicine is an attractive proposition. In the present study, zinc oxide and silver nanoparticles were evaluated for their antidiabetic activity. Fifty male albino rats with weight 120 ± 20 and age 6 months were used. Animals were grouped as follows: control; did not receive any type of treatment, diabetic; received a single intraperitoneal dose of streptozotocin (100...
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BACKGROUND Zinc oxide nanoparticles (NZnO) are increasingly used in modern life. Most metal nanoparticles have adverse effects on the liver. AIMS To explore the protective action of curcumin (Cur) against hepatotoxicity induced by NZnO in rats. STUDY DESIGN Animal experimentation. METHODS Control group animals received normal saline, while the Cur group animals were treated with 200 mg/kg...
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Zinc Oxide nanoparticles (ZnO-NPs) and graphene carbon material, due to lower drug resistance, can replace antibiotics, and by decorating of graphene with Zn-NPs, their properties can be greatly improved. The purpose of this study was to evaluate the antioxidant and antibacterial effects of ZnO-NPs biosynthesized using Crocus Sativus petal extract, graphene and graphene decorated by ZnO-NPs bio...
متن کاملEffects of crocin and zinc chloride on blood levels of zinc and metabolic and oxidative parameters in streptozotocin-induced diabetic rats
Objectives:Crocin is one of constituents of saffron and has antioxidant property. Zinc chloride is one of the common compounds of zinc with antioxidant activity. The present study was aimed to investigate separate and combined treatment effects of crocin and zinc chloride on blood levels of zinc and metabolic and oxidative parameters in diabetic rats. Materials and Methods:Diabetes was induced ...
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Regardless of toxicity of nanoparticles, cerium oxide nanoparticles (CeNPs) are emerging as a multi-functional agent for biomedical purposes. On the other hand, Organophosphorus pesticides, like malathion, are inevitably found in the environment. The common involving pathway CeNPs and malathion share is oxidative stress. Therefore, we conducted this study to find the possible neutralizing or sy...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2015
ISSN: 1530-9932
DOI: 10.1208/s12249-015-0405-y